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The mechanism of hydrogen from Hydrogen Machinery in slowing down aging is mainly achieved through its antioxidant, anti-inflammatory, cell signaling pathway regulation and immune regulation. The following are the specific mechanisms:
1. Antioxidant effect
Hydrogen from Hydrogen Inhlation for Cancer is a selective antioxidant that can neutralize harmful free radicals, such as hydroxyl radicals (•OH) and nitric oxide (ONOO⁻), which are the main causes of cell aging and tissue damage. Hydrogen delays the aging of cells and tissues by removing these harmful free radicals, reducing oxidative stress, and protecting cells from damage.
2. Anti-inflammatory effect
Chronic inflammation is one of the important driving factors of aging. Hydrogen can reduce the damage of chronic inflammation to cells and tissues by reducing the production of inflammatory mediators and reducing inflammatory responses. For example, hydrogen inhalation can reduce the aging and exhaustion of immune cells and restore immune balance.
3. Regulating cell signaling pathways
Hydrogen from White Hydrogen Inhaltion Machine can regulate multiple cell signaling pathways to support cell health and longevity:
Nrf2 pathway: Hydrogen activates the Nrf2 pathway, upregulates the expression of antioxidant proteins and detoxification enzymes, and enhances the antioxidant capacity of cells.
PI3K/Akt pathway: Hydrogen activates this pathway, promotes cell proliferation and prevents cell apoptosis, maintaining cell survival and function.
AMPK pathway: Hydrogen activates AMPK, enhances cell energy metabolism, and ensures that cells have enough energy for repair and maintenance under stress conditions.
4. Immune regulation
Hydrogen can regulate the function of immune cells and reduce the aging and exhaustion of immune cells. For example, studies have found that hydrogen can restore exhausted cytotoxic T cells, reduce the proportion of exhausted PD-1+ CD8+ T cells, and enhance the function of the immune system. This immunomodulatory effect not only helps fight tumors, but may also indirectly delay aging by maintaining a healthy immune system.
5. Protection of cells and organisms
Cellular level: Hydrogen reduces cell aging by regulating the ROS/p53/p21 pathway.
Animal model: Hydrogen can extend the lifespan of Caenorhabditis elegans and Drosophila melanogaster, and improve cognitive function in aged mice.
Human studies: Drinking hydrogen water or inhaling hydrogen can improve characteristics associated with aging, such as reducing inflammatory responses, delaying cognitive impairment, and improving sleep quality.
6. Other mechanisms
Hydrogen can also reduce oxidative stress by regulating mitochondrial function and protecting the antioxidant system in cells (such as coenzyme Q10). In addition, the protective effect of hydrogen on aging-related diseases (such as cardiovascular disease and neurodegenerative diseases) also indirectly reflects its anti-aging potential.
In summary, hydrogen has shown the potential to slow down aging and prolong life through its various mechanisms such as anti-oxidation, anti-inflammation, regulation of cell signaling pathways and immune regulation.