Recent public reports from the Chinese National Health Commission and the Chinese Center for Disease Control and Prevention recommend effective oxygen therapy measures as an element of general treatment for patients with COVID-19 (COVID-19). 1,2 Both documents disclose a rather peculiar proportion of hydrogen and oxygen (66.6% H2 to 33.3% O2) as the composition of the gas mixture for inhalation. Although high oxygen levels are given due to apparent lung dysfunction in COVID-19, mixing with hydrogen for a breathing mixture is still puzzling. Hydrogen is most likely to be added as an inert part of the breathing gas, but it may have beneficial effects in itself. A recent study showed that hydrogen inhibits airway inflammation in patients with asthma, 3 This effect may improve the condition of inflammatory cytokines storms observed in COVID-19. Two multicenter randomized controlled trials (RCT) for COVID-19 inhalation of hydrogen were listed by the World Health Organization (WHO) for clinical trials registered in February and March 2020, but there is no evidence to support this approach. Another factor must be considered: high concentrations of hydrogen may cause static ignition and explosion. Like other promising (and urgently needed) therapies in COVID-19, gas hydrogen therefore requires accelerated but careful research and approval approaches and has sufficient efficacy and safety guarantees. 5 Cutting off the simplest molecules in the universe may be a step back beyond the hydrogen research community of this particular coronavirus.

Hydrogen has been shown to have properties like antioxidant, anti-inflammatory, regulatory hormones, and anti-apoptosis. According to a review of the study, during early COVID-19(coronavirus disease 2019), the use of hydrogen may reduce destructive cytokine storms and lung damage caused by SARS-CoV-2, stimulate viscous sputum drainage, and ultimately reduce the occurrence of serious diseases. Molecular hydrogen therapy has the potential to become a neoadjuvant therapy for COVID-19, but its effectiveness and safety require extensive clinical trials and further validation. Introduction Since novel coronavirus disease (COVID-19) was first reported in Wuhan in late December 2019, it quickly became the sixth largest public health emergency and attracted international attention. As of 11:00 on 31 July 2020,17,328,002 confirmed cases were worldwide, 670,287 deaths, and a total mortality rate of 3.8%. In addition, there were no specific antiviral drugs or vaccines available to prevent COVID-19. Huang found higher plasma IL-2, IL-7, IL-10 and TNF-α concentrations in patients with severe or critical illness than in other patients. This is consistent with Wang shen's pathological results. Therefore, Chen et al. We propose that a cytokine storm is one of the most important factors in critically ill patients. Currently, there are no specific medications available for treating cytokine storms. Hydrogen, a colorless, odorless, tasteless gas, published a 2007 paper in Nature lining that inhaled 2% hydrogen can selectively remove hydroxyl radicals (OH) and ONOO −), significantly improving cerebral ischemia and reperfusion injury in rats and creating a boom in molecular biology research. Based on hydrogen. The biological effects of hydrogen have been widely studied to date. Based on its biological role in antioxidant, anti-inflammatory, anti-apoptosis, and hormone regulation, hydrogen has been determined to protect it on a variety of diseases. In particular, the small molecular properties of hydrogen ensure it is access to the alveolar quickly, suggesting its unique advantage for lung disease. In view of the current prevalence, on the basis of clinical experience, safety, operability and simplicity, this review discusses the feasibility of hydrogen as a means for the control and prevention of COVID-19 by a clinical generalization. Hydrogen and cytokine storms Immune cells can be activated to produce pro-inflammatory cytokines, including tumor necrosis factor- α (TNF-), interleukin (such as IL-1β and IL-6), and interferon- γ (IFN- γ). One role of cytokines is to activate NADPH oxidase in white blood cells resulting in the production of reactive oxygen (ROS) such as superoxides, hydroxyl radicals and monlet oxygen. In 1993, Ferrara et al. The concept of graft resistance against cytokinine storms in host disease was proposed for the first time. The discovery that SARS coronavirus infection induced interferon- γ -related cytokine storms, which may be related to immuno...

Molecular hydrogen is the smallest molecule in the world, but do not be deceived by its size, molecular hydrogen or H2 can be considered one of the most effective antioxidants available that we have. As the first element, hydrogen has been part of the evolution of the cosmic origin. The use of molecular hydrogen to support health has been well studied in both clinical trials and animal studies, and some recent studies involve many topics of interest. The multiple benefits of hydrogen have shown effects affecting detoxification routes, brain health, healthy aging and longevity, affecting post-exercise recovery, and exercise imitation on the body. Let's further explore these concepts as well as the benefits and applications of hydrogen supplementation to achieve optimal health. Today, research shows that the benefits of molecular hydrogen are widely spread as a powerful antioxidant that supports cognitive health and exercise performance, promotes healthy metabolism, and helps activate the body's natural detox system. Molecular hydrogen or diatomom hydrogen consists of two combined hydrogen atoms, consisting of two electrons and two protons, to form a neutral-charged molecule. Due to its lipid soluble and permeability, molecular hydrogen is able to pass through the blood-brain barrier and diffuse through the cell membrane to influence the cytoplasm (intracfluid), mitochondria (energy source of cells) and nucleus ("brain")). In human bodies, hydrogen is a natural byproduct of microbiome fermentation and the development of microbes in the gut; however, production may vary by factors such as personal environment, diet, and overall health. The symbiotic relationship between intestinal health and immune health continues, as studies suggest that molecular hydrogen favors intestinal fermentation and intestinal health, and even promotes the growth of the intestinal flora. Beneficial short-chain fatty acids. Hydrogen gas and detoxification It is well known that hydrogen acts like an adaptation primitive that promotes overall balance in the body and supports a healthy inflammatory response. A number of studies show the therapeutic benefits of molecular hydrogen, used primarily to regulate inflammation and activate the natural detoxification process of the body. The use of molecular hydrogen has also proved protective, as it supports the human body's natural antioxidant pathway expression by activating Nrf2. Another study showed that the use of molecular hydrogen increases antioxidant enzyme activity and reduces TNF-α levels and peroxide levels. In a 4-week randomized, water-added, double-blind, placebo-controlled trial study, antioxidant enzymes were increased. Participants were evaluated at baseline and 4 weeks later, and the men receiving hydrogen-rich water showed increased serum levels for two endogenous antioxidants, superoxide dismutase, and glutathione as compared to a placebo that only received tap water. In addition to antioxidant and detoxification ...

Life is an oxidation process, there are free radicals when there is oxidation, the process of producing energy to produce free radicals, will bring harm to our human body. Free radicals not only come from the body, external air pollution, electromagnetic radiation, pesticide residues, formaldehyde exceeding the standard after interior decoration and bad living habits will produce large toxic free radicals, resulting in the DNA of cells or mitochondria received attacks, causing various diseases. After years of research, Japanese scientists have found that hydrogen is the best antioxidant, adding hydrogen molecules every day, which can scavenge excessive free radicals in the body and selectively resist oxidation. Hydrogen Generator and 6 Efficiency: 1. longevity: the Japan hydrogen research team and the US hydrogen research team have done such an experiment with two identical white mice, and the study found that long-term use of hydrogen water in white mice far longer than ordinary white mice. 2. whitening and freckle: according to many research team experiments, long-term breathing of hydrogen and drinking hydrogen water can effectively enhance skin elasticity, reduce spots, make skin more bright and delicate, desalination dark. 3.Effect of weight loss: according to many years of in-depth research by a team of professors from the Institute of Geriatrics, Japan Medical University, we found that hydrogen has the effect of weight loss, and 4. Anti-Oxidant: research by the institute of Nanjing Medical University has proved that long-term respiration of hydrogen and drinking hydrogen water can improve human antioxidant substances, thus neutralizing malignant reactive oxygen species in the human body and helping to repair human cells. 5.Strengthen immunity:according to the research of the Institute of Medicine, Hiroshima University, Japan, it is proved that breathing hydrogen and drinking hydrogen water can effectively promote collagen synthesis of human fibroblasts, scavenge harmful free radicals, inhibit the death of keratinocytes and improve human immunity. 6.Improve physical condition: hydrogen can improve the condition of chronic diseases that occur in the body. the important effect is to have a good improvement effect on oxidative stress related diseases, such as Alzheimer's disease, Parkinson's disease, diabetes, arteriosclerosis, hypertension, tumor and other major human diseases and allergic problems. Formation and hazards of reactive oxygen species A large part of the oxygen from breathes makes energy in the cell with food. In this process, the oxygen atom has an extra electron state called "reactive oxygen species ", which is unstable and snatches the electrons of other substances, which causes the substance to be oxidized. The harm of reactive oxygen species to the human body is mainly reflected in that it will attack the normal cells. it will attack the DNA genetic factors in the cells and induce cancer, gene mutation, v...